Children aged 0 2 years ie infants with acute myeloid leukemia aml are a peculiar subgroup of patients in the childhood aml scenario they present with distinctive biological and clinical characteristics including a high prevalence of prognostically unfavorable risk factors and an increased susceptibility to therapy related toxicity. Decades of research have led to the accumulation of substantial knowledge about the etiology genetics and molecular and cellular biology of acute myeloid leukemia aml aml is known as the epitome of a stem cell driven malignancy and disease relevant interactions between leukemic stem cells and their specific niche in the bone marrow have . Acute myelogenous leukemia aml is the most common form of leukemia in adults aml is a deadly form of malignancy the prognosis for which has not improved in the last two decades more importantly it is a malignancy that is seen in older adults therefore the number of cases is likely to rise. Acute myeloid leukemia aml is a cancer of the myeloid line of blood cells characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells symptoms may include feeling tired shortness of breath easy bruising and bleeding and increased risk of infection. Buy acute myelogenous leukemia genetics biology and therapy cancer treatment and research book 145 read kindle store reviews amazoncom
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